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Acknowledgements The authors' research was supported by the grants FIS PS09/00447, PI13/00047, ISCIII-RETIC REDinREN RD12/0021, Comunidad de Madrid S2010/BMD-2378, and CYTED IBERERC, by Programa Intensificacin Actividad Investigadora (ISCIII) to A.O., by ERAEDTA fellowship to L.G.E

Rather than serving as a first-line treatment, it is typically considered an adjunctive therapy that may complement more established approaches, such as physical therapy, exercise modification, and other evidence-based interventions

Our approach involves using GLP-1 receptor agonists to mimic the effects of the GLP-1 hormone, thereby regulating appetite and food intake to facilitate significant weight reduction

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