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Although our study used YF17D exclusively, our findings may extend to other forms of vaccine: Clinical studies in T2DM patients reveal that patients on chronic metformin therapy exhibit diminished antibody responses following TIV vaccination compared to non-metformin users, irrespective of their glycemic control (Agarwal et al, 2018

GLP-1R, a key member of the G protein-coupled receptor family, is ubiquitously expressed on the surfaces of various cells, such as pancreatic -cells, hepatocytes, and cells in the cardiovascular and neural systems, and has significant therapeutic potential for multiple diseases

2.2 Loop-diuretics The story of loop diuretics began in the early 1960s, when ethacrynic acid was found to increase urine production in both animals and humans (Beyer et al., 1962

Biochem Pharmacol (2021) 190:114661