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Unlike the case of the glutathione production by l-Ser biosynthetic gene overexpressing strains, the results of the strains overexpressing SHM2 and/or CYS4 using GCI/Vector, GCI/ SER3 , and GCI/ SER33 as platform strains were complicated

[77] In diabetic kidney disease, a Phase 1 open-label trial following a similar intermittent D + Q treatment procedure (NCT02848131) reduced senescent cell count in skin epidermal and adipose tissues and lowered circulating SASP factors