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PubMed PMID: 18670186 Mitochondrial function Mitochondrial glutathione: features, regulation and role in disease

Plan for about 75 minutes total including check-in, preparation, and post-treatment monitoring

Marins 3 , Kaili Ren 3 , Marco Vilela 3 , Thikshaya Mahendran 4 , Amanda Sees 2 , May Hagiwara 3 and Rohit Loomba 5 , (1)University of Florida, Gainesville, FL, USA, (2)Iqvia, Plymouth Meeting, PA, USA, (3)Takeda Development Center Americas, Inc., Cambridge, MA, USA, (4)Iqvia, Bengaluru, India, (5)University of California, San Diego, San Diego, CA Background: Diagnosis (dx) of alpha-1 antitrypsin deficiency (AATD)-associated liver disease (LD) is challenging due to the variable risk and asymptomatic nature of the disease

Distinction of sporadic and familial forms of ALS based on mitochondrial characteristics