glutathione enhancer uses in Our Diet and Its Role in the Body: From Disease Prevention to Anti-Aging Glutathione for the skin |

In a recent study, Epimedium brevicornum, mainly composed of Epimedium brevicornum polysaccharides, was found to promote bone formation and ameliorate apoptosis by regulating the Bax/Bcl-2 signaling pathway, thus accelerating osteogenesis in osteoblasts in a HG-induced DOP model (Lei et al., 2023)

In RA, reduced mitochondrial DNA biostability and mtDNA leakage into the cytoplasm due to the lack of DNA repair nuclease (MRE11A) increase the pro-inflammatory tendency of T-cells, whereas upregulation of MRE11A expression reduces mitochondrial damage and has an inhibitory effect on T-cell scorching and immune inflammation (32, 75)

Szablewski L

Mechanisms proposed include the preservation of mitochondrial function and reduction of reactive oxygen species (ROS) accumulation