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However, ISA was identified as inhibitors of Nur77 and Nurr1, indicating its neuroprotection was not mediated by Nur77 and Nurr1 (Jung et al., 2019

There is no universally accepted, evidence-based public standard for injectable GHK-Cu dosing, and protocols vary widely by clinic

Induction of these genes is known to be highly protective against APAP toxicity [119]

Moreover, decreasing the levels of intra-lysosomal cystine by cysteamine did not alter this mechanism and thus CTNS itself and not cystine is likely to be responsible for the activation of this pathway [38]