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13 In this observational noncontrolled study, 12 patients with COVID-19 pneumonia and risk factors for poor outcome were treated with 3 doses of lenzilumab, and clinical improvement was noted in 92% with a median time-to-discharge of 5 days

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A subsequent multicenter Phase 2 trial in participants with overweight or obesity reported approximately 15.6% mean body weight reduction at 32 weeks with cagrilintide 2.4 mg plus semaglutide 2.4 mg, compared to roughly 5.1% with placebo and lower percentages with either monotherapy