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Reconstruction and analysis of the genome-scale metabolic model of Lactobacillus casei LC2W

Abstract Riboflavin deficiency is widespread in many regions over the world, especially in underdeveloped countries

However, these models fail to explain how disease-specific monomeric Syn variants orchestrate the sequestration of diverse cellular proteins and damaged membrane organelles to initiate and promote LB formation

Niacin, a key agent in lipid regulation, has demonstrated beneficial effects on apolipoprotein B-containing and apo A-I-containing lipoproteins, correlating with decreased nuclear cataract incidence in initial studies (26)