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130 In fact, some data from non-human primate studies indicate that adenosine receptor antagonists, like caffeine, may allow for a reduced dosage of L-DOPA

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Rg1 significantly downregulated M1 macrophages and upregulated M2 macrophages to modulate the balance between macrophage M1/M2 polarization [254]

This makes it a key peptide for studying metal-peptide interactions and redox-based signaling mechanisms

If the patient declines buprenorphine or methadone therapy, then they may be treated with shorter-acting full opioid agonists to prevent withdrawal (e.g., IV morphine or oral morphine IR as needed)