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[DOI] [PubMed] [Google Scholar] 148.Hulley S, Furberg C, Barrett-Connor E, Cauley J, Grady D, Haskell W, Knopp R, Lowery M, Satterfield S, Schrott H, Vittinghoff E, Hunninghake D, Group HR Noncardiovascular disease outcomes during 6.8 years of hormone therapy: Heart and Estrogen/progestin Replacement Study follow-up (HERS II) JAMA

Thus, variants in other genes could contribute to this disorder, especially those genes and their protein products within the pathway that process trimethylamine in the same or a similar manner as the FMO3 enzyme

MOA Methionine An essential sulfur-containing amino acid, methionine undergoes transmethylation reactions to generate metabolic by-products including S-adenosyl methionine (SAM) and homocysteine