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Description

871 Oxidative stress is characterized by MDA and 4-HNE, and their roles in cartilage degeneration and subchondral bone remodeling during OA development have received extensive attention

Segal R, Mozes E, Yaron M, Tartakovsky B: The effects of methotrexate on the production and activity of Il-1

Mice were used under the protocols M1900034, V1800106, and V2000018 approved by the IACUC at Vanderbilt University and Institutional Biosafety Committee and the Research and Development Committee of the Veterans Affairs Tennessee Valley Healthcare System