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Multiple purposeA clinical test for CD53 is available in the NIH Genetic Testing Registry The term "FERMT 3" refers to Fermitin family member 3, and belongs to a small family of proteins that mediate protein-protein interactions involved in integrin activation and thus have a role in cell adhesion, migration, differentiation and proliferation

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Prevalence varies substantially by ancestry null frequencies reach 5060% in some East Asian populations and are approximately 2030% in African-ancestry populations in most published frequency estimates

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