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10.1038/s41571-023-00815-5 91 RahaD.WilsonT

Looking at uric acid a little bit more broadly now with the with the kind of diets that we've talked about traditionally when trying to reduce one's uric acid level, usually in the hope that their gout gets better or we can optimize with allopurinol

Glutathione Promotes Sperm Vitality and Motility Egg cells need protection, but so do sperm cells

Pre-treatment of HGF with trisulfides and nitration Recombinant mouse HGF (carrier protein-free) was pre-treated with glutathione trisulfide (GSSSG) and lipoic acid trisulfide (LASSS) at mole ratios (HGF : trisulfide) of 1:0 (with solvent alone), 1:400, 1:1000, and 1:4000 at pH 7.4, 25C just prior to the peroxynitrite protocol (optimized at a molar ratio 1:2000 relative to HGF, pH 7.4, 37, for 30 min), which was previously demonstrated to induce maximal nitration of Y198 and Y250 located in the -chain under physiological conditions as described previously 32