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Thirdly, lactate can function as both an energy substrate and a signaling molecule, engaging in lactate shuttling (intra- or intercellular lactate exchange)

It is vital for the functioning of muscles, the nervous system, and the heart

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Particularly noteworthy is the finding that genetic polymorphisms of complement components C4A and C4B are significantly associated with various microbial environmental variables in schizophrenia patients, including a history of pathogen exposure and gut ecological imbalance (143)