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GPx enzymes are essential for maintaining redox balance by reducing H 2 O 2 and organic hydroperoxides to water and alcohols, using reduced GSH as a cofactor [71]

The GSH to glutathione disulfide ( GSSG ) ratio is a key indicator of cellular oxidative stress, highlighting the importance of maintaining balanced levels

Goswami, S, Gao, J, Basu, S, Shapiro, DD, Karam, JA, Tidwell, RS, Ahrar, K, Campbell, M, Shen, Y, Trevino, AE, Mayer, AT, Espejo, A, Seua, C, Macaluso, M, Chen, Y, Liu, W, He, Z, Yadav, SS, Wang, Y, Rao, P, Zhao, L, Zhang, J, Jindal, S, Tannir, NM, Futreal, A, Wang, L , Sharma, P

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