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Science 265(5174):956959 Kressler J, Mendez A, Betancourt L, Nash M (2023) Salsalate improves postprandial glycemic and some lipid responses in persons with tetraplegia: a randomized clinical pilot trial with crossover design

Balanced energy rhythms are essential for a well-functioning biological clock, which regulates sleep, hormone release, and daily alertness

While systemic dihexa half life remains one to two hours, CNS concentrations may persist for four to six hours because the peptide is delivered to the target site without requiring blood-brain barrier penetration

In this study, participants receiving ALA showed a marked reduction in the Neuropathy Symptoms Score compared to those who did not receive treatment, the patients treated with ALA reported an average time of 18.4 days for symptom relief (Pieralice et al., 2019)