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An updated review of Chinese skullcap (Scutellaria baicalensis): emphasis on phytochemical constituents and pharmacological attributes

A notable exception to this biosynthetic capability are the nematode Caenorhabditis elegans and other parasitic helminths, which are heme auxotrophs 25

After treatment, the PC12 cells were added with 100 M cycloheximide to interfere with the translocation step in protein synthesis

Notably, the substitution of the Cys351 site of PFKM with alanine significantly decreased the proliferation rate of ovarian cancer cells overexpressing nitric oxide synthase, highlighting the critical role of the Cys351 site in PFKM SNO modification [89]