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early and prolonged application of a GSH infusion improved cardiac repair and prevented infarct expansion in patients with myocardial infarction undergoing primary percutaneous coronary intervention [5]

[DOI] [PubMed] [Google Scholar] Victor VM, De La Fuente M

Abnormalities in the mitochondrial electron transport chain (ETC), combined with impaired antioxidant defenses, lead to excessive accumulation of reactive oxygen species (ROS), which damage lipids, proteins, and mitochondrial DNA, ultimately promoting tubular apoptosis, interstitial fibrosis, and glomerulosclerosis ( Vitamin D mitigates oxidative stress and mitochondrial damage through multiple mechanisms