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This inhibitory action was attributed to Norleual-AngIVs capacity to prevent HGF dimerization, a crucial step for c-Met activation, while Dihexa was subsequently confirmed to act as an agonist within this system

(5/9/14) NOTE: This is the working draft of a self study on pharmacokinetics that will cover the basic concepts that are important for both USMLE Step 1 and clinical practice