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To evaluate patient-reported effects of treatments, we defined a NAS based on patients responses on the impact of each treatment on their overall condition: The number of positive and negative feedback corresponds to patients reporting any level of improvement or worsening, respectively

Also noteworthy is that NAC-S2 inhibited not only INF-I- but also IFN--induced signaling, which highlighting the broader immunomodulatory potential of supersulfides ( Figure 7 )

Inflammasome activation triggers the influx of sodium ions and water-mediated by gasdermin D, resulting in pyroptosis and the maturation and release of cytokines