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When individuals have low B12 levels, they often experience severe fatigue, weakness, and depression [Kenneth Goodman, MD, 2024]

Advise patients using oral hormonal contraceptives to switch to a non-oral contraceptive method or add a barrier method of contraception for 4 weeks after initiation and for 4 weeks after each dose escalation with MOUNJARO [see Drug Interactions (7.2), Use in Specific Populations (8.3), and Clinical Pharmacology (12.3)]

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The guidelines are for people at high risk to be screened with a routine blood test at least once a year