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The most common one, is known as post-inflammatory hyperpigmentation (PIH), a term refers to discoloration that shows up on the skin as a result of an inflammatory response to some form of trauma

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doi: 10.1176/appi.ajp.159.8.1354

The AAV/IGF2BP2 attenuated paw edema, synovial hyperplasia and cartilage destruction by reducing the expression of MMPs in vivo , and inhibited the migration and invasion of RAFLSs (132)