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Beyond angiogenesis, BPC-157 also modulates the nitric oxide system (which plays a role in tissue protection), increases FAK-paxillin expression (involved in cell adhesion and growth), and has been shown in animal studies to reduce inflammatory cytokines

D.HsiaA.IzumiyaY.WuC.et al (2011)

Qu J, Yan H, Hou Y, Cao W, Liu Y, Zhang E

And this occurred during a switch from Detroit water that the city been using for a period of decades to Flint River water which runs through the town - it's a little bit of a saltier water source, a little more corrosive - and once that water was put into the system, a perfect storm of corrosion was unleashed