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A key regulator of NRF2 activity is kelch-like ECH-associated protein 1 (KEAP1), which acts as a ROS sensor and principal suppressor of NRF2

Incubation of porcine aortic endothelial cells with Hcy also caused a significant time-dependent increase in the concentration of O 2 released by these cells

10.3390/ijms22094691 [DOI] [PMC free article] [PubMed] [Google Scholar] 271.Martnez-Salazar B, Holwerda M, Stdle C, Piragyte I, Mercader N, Engelhardt B, et al

7.1.4 Probiotics and inflammasomes: balancing inflammation and antiviral defense Inflammasomes are sophisticated intracellular multiprotein complexes that function as master regulators of innate immunity (233)