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The fundamental caveat to this theory is that the amount of ROS-mediated damage required to shorten lifespan is usually never achieved without exposure to toxins or radiation 6

10.1042/BJ20110326 113 SaidH

Relationship between heat stress during the peri-implantation period and early fetal loss in dairy cattle

J Neurosci Res 102(1):e25281 Lee SH, Kim HS, An YS, Chang J, Choi J, Im GJ (2015) Protective effect of resveratrol against cisplatin-induced ototoxicity in HEI-OC1 auditory cells