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239 In murine models, enterotoxigenic strain colonization can induce colitis and promote colorectal carcinogenesis through the IL-17R, NF-B, and STAT3 pathways

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In tumors with heterogeneous or low antigen expression, membrane-permeable payloads, including SN-38 and deruxtecan, are capable of diffusing into adjacent antigen-negative cells, thereby mediating a bystander effect that amplifies therapeutic coverage across spatially diverse tumor cell populations [47, 122, 124]

It is believed that these microclots contribute to both thromboembolic events seen in severe COVID-19 patients and the prolonged symptoms seen in patients with long COVID-19 [5]