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3.6 6-Gingerol reduced placenta dysfunction, mitochondrial damage, and apoptosis in PE-like mice To verify the effect of 6-gingerol on placenta injury of PE in vivo , a mouse PE model was established by an intraperitoneal injection of L-NAME, which caused fetal growth restriction (FGR), hypertension, and other symptoms of PE

The expression of lncRNA SEMA5A-IT1 in serum small circulating extracellular vesicles of patients after CPB is higher than that before CPB, which is inversely proportional to the level of creatine kinase-MB

3.2.4 SUMOylation SUMOylation, a reversible PTM of p53, has attracted increasing attention because it occurs in almost all eukaryotes (Figure 4D)

188 LCN2 inhibits ferroptosis by enhancing GPX4 and SLC7A11 expression and reducing intracellular iron levels, and LCN2 overexpression in colon cancer cells leads to resistance to 5-fluorouracil (5-FU) by inhibiting ferroptosis