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Inhibiting CHAC1 could disrupt these pathways, leading to unintended consequences such as impaired cellular stress responses and the potential exacerbation of oxidative damage in non-target tissues

Liver zonation: novel aspects of its regulation and its impact on homeostasis

Thadtapong N, Chaturongakul S, Napaswad C, Dubbs P, Soodvilai S

Regional prevalence rates are currently highest in the Middle East (32%) and South America (30%) and lowest in Africa (13%), but prevalence rates are even higher in specific subpopulations such as severely obese (90%) and patients with type 2 diabetes (76%) [1]