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Alpha Arbutin works effectively to reduce the appearance of dark spots and pigmentation, while Niacinamide supports skin barrier function and enhances overall skin clarity

10.1016/j.phrs.2019.104511 94

225 Administration of the PRMT4 inhibitor TP-064 in a mouse model of atherosclerotic cardiovascular disease can induce a decrease in monocyte tumor necrosis factor- (TNF-) secretion, downregulate the gene expression of the glycogen metabolism-related protein G6pc in the liver, and reduce plasma triglyceride levels, exerting regulatory effects from inflammatory and metabolic pathways