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Description

Opioid receptor modulation of hedonic taste preference and food intake: a single-dose safety, pharmacokinetic, and pharmacodynamic investigation with GSK1521498, a novel mu-opioid receptor inverse agonist

These compounds can act as direct antioxidants by scavenging free radicals and chelating metal ions, as well as indirectly by upregulating endogenous antioxidant enzymes and modulating cellular signaling pathways involved in the oxidative stress response

(2010) in the BBB of mice

For example, in Section E we showed that moderate oxidative stress causes blood GSH and blood cysteine to rise, but severe oxidative stress causes blood GSH and blood cysteine to fall