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Importantly, these symptoms can occur with or without anaemia and/or macrocytosis

Other conditions that make Vitamin B12 absorption more difficult are: Weight loss surgery or another operation that removed part of your stomach Heavy drinking Taking acid-reducing medication for a long time Certain health issues may also lead to the development of vitamin B12 deficiency such as atrophic gastritis, pernicious anemia, Crohns disease, celiac disease, immune system disorders, Graves disease and lupus

NB, like other malignancies, is associated with modifications in cellular metabolism that may contribute to oncogenesis

Scale Weight: While less informative than body composition, weekly weigh-ins (same day/time, fasted) establish trends