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Among them, the Phi class (GSTF) is composed of a large number of genes that are often induced in response to environmental constraints due to their ability to detoxify xenobiotics, to their peroxidase activity and to their involvement in the biosynthesis and/or transport of secondary metabolites

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[DOI] [PubMed] [Google Scholar] 41.Wang L.I., Giovannucci E.L., Hunter D., Neuberg D., Su L., Christiani D.C

39 Many physiological processes require iron, but iron overload produces toxic effects because excessive free iron can easily change between trivalent and bivalent forms