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Oxidation and poor glycosylation of band 3 further facilitates clustering of this protein (Pantaleo et al., 2009)

Recent studies have shown that the mechanism underlying ferroptosis involves an imbalance of the cell redox system caused by iron-mediated toxic phospholipid hydroperoxide (PLOOH) metabolism disorders, which eventually cause oxidative damage to the cell membrane and proteins

Furthermore, it influences immune function by modulating CD4 + T cell and Treg cell activity to suppress systemic inflammation

Curcumin decreases the toxicity of Syn aggregates in PD by altering their hydrophobic surface exposure [234]