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Preliminary data have shown that this drug could be effective also in acquired HO [119] and a prospective, randomised, blinded trial over a 12-month treatment period is ongoing to better define its promising role in this clinical setting (NCT05774756)

Activation of Rho-associated coiled-coil protein kinase 1 (ROCK-1) by caspase-3 cleavage plays an essential role in cardiac myocyte apoptosis

On other hand, patients with CFS exert significant effort to perform their daily activities, resulting in enhanced neural activation which may boost the production of pro-inflammatory cytokines and reactive oxygen and nitrogen species (Lange et al

Human seroprevalence of Borrelia miyamotoi in Manitoba, Canada, in 2011-2014: a cross-sectional study