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The resolution of inflammation characterizes a shift from a pro-inflammatory state to the anti-inflammatory phase, followed by repair and regeneration of injured tissues, processes markedly played by macrophages that include angiogenesis, matrix remodelling, and establishment of homeostasis [71]

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Transitioning to maintenance therapy entails clinical and biochemical monitoring in the first 26 months (as opposed to standard 6month intervals) to ensure effective therapy

Quickstart Highlights Cagrilintide is a longacting acylated analogue of the pancreatic hormone amylin, designed for onceweekly subcutaneous administration [1]