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First, participant selection should clearly define diagnostic criteria for the disease, including both early- and mid-to-late-stage AD patients, while excluding those with severe comorbidities or immune system abnormalities to ensure consistency and safety

A clinical study in healthy volunteers found that 1-deoxynojirimycin-enriched white mulberry powder suppressed post-prandial blood glucose surge and lowered insulin levels (Kimura 2007)

Preclinical studies show that HG can reduce the infiltration of leukocytes by downregulating adhesion molecules and chemokines, leading to less inflammation and potentially less tissue damage in many critical conditions [8,9,10, 20, 32]