l carnitine ubidecarenone zinc lycopene and astaxanthin L-Carnitine Tablets, 500 mg at ₹ 349/box in Panchkula Private Label Infertility & PCOS

The mechanism operates through upstream modulation of inhibitor of kappa B (IkB) kinase activity, which normally phosphorylates and degrades IkB proteins, freeing NF-kB to drive inflammatory gene transcription

Initial management focuses on lifestyle modifications, including dietary changes, weight loss, and regular aerobic exercise, which directly improve peripheral insulin sensitivity

doi: 10.3389/fgene.2015.00042 29 HaiderA.KangI.-K

Mutations in the GTPases optic atrophy 1 (OPA1) and Mfn2 are associated with autosomal dominant optic atrophy and Charcot-Marie-Tooth neuropathy type 2A, and suggest a role for abnormal mitochondrial fusion in the pathogenesis of these human diseases (Larrea et al., 2019)