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Am J Physiol - Cell Physiol (1987) 253:C85461

The timing of bedtime is deliberate: GH secretion is most active during slow-wave sleep, and dosing sermorelin to coincide with that window is standard clinical practice to achieve the best response from the pituitary

Such a registry will provide information about the natural course of the disease and information about treatment interventions found to be effective could provide a basis for future clinical trials