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Description

Nature 458 , 11311135 (2009)

Without adequate acid, this step fails, and the B12 stays locked to the food, unable to be absorbed

I'm not medically trained just someone who suffered for years from unrecognised and untreated B12 deficiency

However, N-terminal modifications, such as N-acetylation, D-norleucine substitution, or replacement with -aminobutyric acid (GABA), dramatically elongated the peptides half-lives