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Stahl S (2022) Stahls essential psychopharmacology: prescribers guide

The liver responds to GH by producing IGF-1 , and IGF-1 is what actually drives the downstream tissue effects clinicians associate with growth hormone protein synthesis, satellite-cell activation for muscle repair, lipolysis, collagen synthesis, and bone remodeling

When introducing any IV fluids to the system, careful calculations must be made to ensure that the administered solution is of a comparatively similar electrolyte concentration to the body to maintain this equilibrium