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doi: 10.1603/0022-0493-98.3.656 73

In the multivariate Cox regression analyses, crude favorable prognostic factors included a good ECOG-PS before pemetrexed exposure, BMI 20.66, FA level 5.55 ng/mL before premedication, higher serum RBP level before pemetrexed treatment, SI G) (Supplementary Table S5(a))

Weight loss Investigated in clinical trials for substantial weight reduction as a triple agonist

FOXO4-DRI Human Trials: Status, Evidence Gaps, and What to Watch (2026) As of July 2026, no human trial of FOXO4-DRI has ever been registered or published