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S.KarryR.RobicsekO.AberdamE.MullerF

Devries, M

Structural understanding of disease/drug resistance-related androgen receptor mutations through X-ray crystallography and structural modeling Because the AR remains the driving force in the progression of more aggressive castration-resistant prostate cancers 139 , it is important to understand how each genetic aberration affects the pharmacology of the AR and its ligands