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systemic therapies are candidates for advanced settings, whereas best supportive care is most appropriate for end-stage of HCC (Llovet et al., 2021)

The opposite role of lactate dehydrogenase a (LDHA) in cervical cancer under energy stress conditions

Common Symptoms of B12 Deficiency The signs of deficiency can vary but often include: Chronic fatigue Tiredness that doesnt improve with rest Brain fog Poor memory, lack of concentration, confusion Mood changes Depression, irritability, or anxiety Numbness or tingling Especially in hands and feet Pale or yellowed skin Muscle weakness Balance issues or dizziness Shortness of breath In severe cases, untreated deficiency can lead to irreversible nerve damage and anemia

[DOI] [PubMed] [Google Scholar] Gerdes S.Y., Kurnasov O.V., Shatalin K., Polanuyer B., Sloutsky R., Vonstein V., Overbeek R., Osterman A.L