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Similar to the breast cancer model, anti-VEGF and imatinib combination markedly induced cellular apoptosis in FGF-2 + fibrosarcomas, which otherwise were completely resistant in their monotherapy settings (Fig

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Francisco Triana-Martnez et al., in their research, administered gemcitabine alone (25 mg/kg, IP), digoxin alone (2 mg/kg, IP), or a combination of both drugs at the same doses through intraperitoneal injections to immunocompromised mice that had previously been subcutaneously injected with A549 lung adenocarcinoma cells [140]