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Structure, Function, and Post-Translational Regulation of the Catalytic and Modifier Subunits of Glutamate Cysteine Ligase

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As Diana Isaacs, PharmD, from Cleveland Clinic explains: "If you don't have enough vitamin B12, that can lead to neuropathy, or the numbness and tingling of your hands and feet and can even cause memory problems." Diana Isaacs, PharmD, Cleveland Clinic This deficiency can also result in pernicious anemia, marked by a lack of healthy red blood cells

The expanded erythron can cause absorption of excessive dietary iron and hemosiderosis, even without transfusion