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OASIS was used to annotate the top SNPs with position, chromosome, allele frequencies, closest gene, type of variant, position relative to the closest gene model, and other information

The L-carnitine-supplemented group showed a dose-dependent reduction in the levels of ACE2, TMPRSS2 and furin with the maximum effect observed at 200 mg/kg/day, which translates to 2,000 mg HED

Based on the above research and analysis, it has been found that the high-altitude, low-pressure and low-oxygen environment may have a significant impact on the health of the male reproductive system, resulting in a decrease in the number of sperm, reductions in sperm motility and viability, an increase in the rate of sperm abnormalities, an increase in germ cell apoptosis and increased disorders of sex hormone secretion [54, 55]

The Unfolded Protein Response and Hepatic Lipid Metabolism in Non Alcoholic Fatty Liver Disease