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TMD can cause the jaw to lock or become trapped in one position or another

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NMDA-R de-sensitize more slowly than AMPA-R and KA-R

, ID 1 mg/kg :3 5(0.15%), 50 mg/kg ( 5).In the second rat ID study, the most effective permeation enhancer (PE) tested for a 1 mg/kg dose of SEQ ID NO: 3 peptide was a combination of 50 mg/kg sodium kenodeoxycholate and 25 mg/kg propyl gallate Was found, which increased the oral bioavailability of the SEQ ID NO: 3 peptide by about 20-fold to 0.39% (Table 6)