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Puffing on slim metal tubes loaded with pale yellow liquid, two London businessmen say they have between their lips a cure for what the UN calls one of the biggest public health threats the world has ever faced. Electronic cigarettes are the future, they argue

What began as a simple idea to provide a safer alternative to traditional smoking has evolved into a multi-billion pound global industry that has fundamentally changed how millions of people consume nicotine

Additionally, aerosolized nicotine from vaping has been linked to increased thromboembolic activity and impaired dilation and relaxation of small blood vessels ( Given the ongoing debates about the health implications of electronic cigarette use, this systematic review aims to thoroughly investigate the direct effects of electronic cigarette use on human health, considering the characteristics of the populations studied and the duration of exposure