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OhlenbuschAEdvardsonSSkorpenJBjornstadASaadaAElpelegOet al

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Effect of calorie-unrestricted low-carbohydrate, high-fat diet versus high-carbohydrate, low-fat diet on type 2 diabetes and nonalcoholic fatty liver disease : a randomized controlled trial

Given these relationships it seems likely that the reduced level of hepatic Scd-1 expression observed in Tg-I278T Cbs / mice is at least in part responsible for the reduction in fat mass