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discovered the presence of UCP1 in human BAT [75]

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[10] [12] Concomitant use with aluminum-containing antacids may increase aluminum absorption, especially in patients with renal impairment

Interestingly, microbial metabolism also has a strong impact on cytokine production, which is mainly mediated by the tryptophan metabolite tryptophol that has strong inhibitory effects on the TNF- response [121]